Tabla de posiciones- Torneo apertura 2021-2022
| Pos | Equipo | PJ | PG | PE | PP | GF | GC | DG | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Real España | 18 | 11 | 5 | 2 | 32 | 15 | 17 | 38 |
| 2 |  Vida | 18 | 10 | 6 | 2 | 30 | 17 | 13 | 36 |
| 3 |  Olimpia | 18 | 10 | 5 | 3 | 35 | 14 | 21 | 35 |
| 4 |  Motagua | 18 | 10 | 5 | 3 | 37 | 20 | 17 | 35 |
| 5 |  Lobos UPN | 18 | 7 | 6 | 5 | 28 | 21 | 7 | 27 |
| 6 |  Marathón | 18 | 8 | 3 | 7 | 25 | 19 | 6 | 27 |
| 7 |  Real Sociedad | 18 | 4 | 4 | 10 | 19 | 41 | -22 | 16 |
| 8 |  Honduras P. | 18 | 4 | 3 | 11 | 19 | 30 | -11 | 15 |
| 9 |  Victoria | 18 | 4 | 2 | 12 | 10 | 32 | -22 | 14 |
| 10 |  Platense | 18 | 1 | 3 | 14 | 19 | 45 | -26 | 6 |
